What Are Probiotics
According to the World Health Organization (WHO) probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host.” There are numerous factors that can disturb your intestinal balance and decrease the level of beneficial bacteria in your gut such as: Poor diet, Age, Illness, Hormonal change, Travel, Stress, Antibiotics, Medications, Changes in diet. Taking a probiotic can help keep you balanced. And with an astounding 70% of your immune system in your digestive system, it makes sense that a healthy digestive system supports a healthy immune system.
GanedenBC30 (Bacillus coagulans GBI-30, 6086) is an EXTREMELY stable probiotic due to the cell’s ability to form a protective spore. Just like seeds wait to grow when conditions are optimal, GanedenBC30 spores wait to germinate until they reach the intestines where the moisture level, temperature and nutrient levels are just right. This protective shell also gives GanedenBC30 the ability to survive: Harsh manufacturing processes, Product shelf life, The journey through the digestive system. Many probiotics, such as those used in yogurt, are vegetative (ex. Lactobacillus and Bifidobacterium) and just can’t survive these stresses.
What is the difference between GanedenBC30 and other spore-forming probiotics?
When comparing GanedenBC30 to other spore formers you need to ask if it is safe for everyone and do they have strain-specific data to support the efficacy of the exact strain. B. subtilis for example is contraindicated for use in immuno-compromised populations, while GanedenBC30 can be used by virtually anyone. Efficacy of a probiotic is strain specific, and just because a stain may be of the same genus and species, does not mean that they have the same effect. To date, there are 24 published papers that support the safety and efficacy of GanedenBC30, while other spore forming Bacillus coagulans have little to no data on their strain.
Why only 1 Billion CFUs? My probiotic pills have 50 Billion!
The benefits of all probiotics are 100% strain specific. Some strains may require an intake of 10 billion, 50 billion or even more in order to confer a specific health benefit, while GanedenBC30 has been shown, in peer-reviewed papers, to support immune health at 500 million CFU per day and support digestive health and protein utilization at 1 billion CFU. More is not always better!
24 published studies & counting
A patented strain of Bacillus coagulans increasedimmune response to viral challenge. Postgraduate Medicine, 2009; 121 (2): 114-118 Mira Baron Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS. Postgraduate Medicine, 2009; 121 (2): 119-124b Larysa Hun Safety assessment of a proprietary preparation of a novel probiotic, Bacillus coagulans, as a food ingredient. Food and Chemical Toxicology, 2009; 47: 1231-1238. (First ever published study on safety of Bacillus coagulans) J.R. Endres, A. Clewell, K.A. Jade, T. Farber, J. Hauswirth and A.G. Schauss A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms. BMC Gastroenterology, 2009; 9:85. Douglas S. Kalman, Howard I Schwartz, PAtricia Alvarez, Samantha Feldman, John C Pezzullo and Diane R Krieger Effects of a proprietary Bacillus coagulans preparation on symptoms of diarrhea-predominant irritable bowel syndrome. Methods Find Exp Clin Pharmacol. 2009; 31(10):655-659 B.J. Dolin Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine. Beneficial Microbes, 2010; 1 (1): 31-36. A.J. Maathuis, D. Keller and S. Farmer Bacillus coagulans: A viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complementary and Alternative Medicine 2010; 10:1 David R Mandel, Katy Eichas and Judith Holmes
GanedenBC30 cell wall and metabolites: anti-inflammatory and immune modulating effects. BMC Immunology, 2010; 11:15 Gitte S Jenson, Kathleen F Benson, Steve G Carter and John R Endres A controlled clinical trial to evaluate the effects of GanedenBC30 on immunological markers. Methods Find Exp Clin Pharmacol. 2010 32(2) 129-132 M. Kimmel, D. Keller, S. Farmer and D.E. Warrino